Collect compounds throughout the environment to process in your cell's organelles and generate ATP. Be careful not to let your ATP stores run out, or you will slow down, lose health and eventually die.

The various compound clouds are:

White – Glucose
Yellow – Hydrogen Sulfide
Orange - Ammonia
Purple - Phosphates
Rust Brown - Iron Ions

Glucose makes ATP
Hydrogen Sulfide can be converted into glucose via chemoplasts and chemosynthesizing proteins
Iron Ions can be converted via rusticyanin into ATP
and Ammonia and Phosphates are crucial for reproduction.

Press E to release a dangerous agent, Oxytoxy NT, to kill other cells and then collect the spilled compounds if you have a toxin vacuole.

You can also engulf cells and bacteria and iron chunks and cell chunks that are smaller than you by pressing G. This will cost additional ATP and will slow you down. Don't forget to press G a second time to stop engulfing.

To reproduce you need to divide each of your organelles into two and then duplicate the DNA in your nucleus. Each organelle needs 2 ammonia and 2 phosphate to split in half.

Osmoregulation Now costs ATP, which means the bigger your cell is, the more Mitochondria or Metabolosomes or Rusticyanin (or cytoplasm, which does Glycolysis) you need to avoid losing ATP when you are stationary. It works this way: Osmoregulation costs are ((Hex Amount * 1) per second...

There are many Organelles in the editor for you to evolve, allowing for a wide range of different playstyles.

For this Release if your population (top tab) drops to zero you go extinct.
But if you survive for fifteen generations with 200 population, you are considered to have won, after winning you get a popup and can continue playing as you wish.

Be wary because your competitors are evolving alongside you. Every time you enter the editor they evolve as well.

Every time you reproduce, you will enter the Microbe Editor, where you can make changes to your species (by adding, moving, or removing organelles) to increase your species' success.

Each visit to the editor in the Microbe Stage Represents 200 million years of evolution
Each generation, you have 100 mutation points to spend, and each change (or mutation) will cost a certain amount of that MP, removing costs mutation points aswell as adding.

You can rotate your organelles, with A and D

Prokaryotic Structures
Metabolosomes: Produces the same amount of ATP of a mitocondria, but is way way less efficient, it only takes up 1 Hex
Chemosynthisizing Proteins: Produces half of the glucose out of Hydrogen Sulfide as a chemoplast, but also performs glycolysis, takes up 1 Hex
Chromatophores: Produces 1/3rd the amount of glucose as a normal chloroplast, but also performs glycolysis, and takes up 1 Hex.
Rusticyanin: Converts iron ions into ATP, and takes up 1 Hex.
Nitrogenase: Converts atmospheric nitrogen and ATP into ammonia anaerobically
Cytoplasm: Increases the rate of compound absorbtion and has 4 storage space and performs glycolysis (Produces small amounts of ATP).

External Organelles
Flagella: Moves your cell faster by consuming ATP.
Pilus: Can be used to stab other cells.

Membrane Bound Organelles
Nucleus: Takes up 11 hexes and allows for evolution of membrane bound organelles. And also doubles your cells size. (Can only be evolved once)
Mitochondrion: Produces ATP out of glucose and atmospheric 02. Much more efficiently then cytoplasm
Chloroplast: Makes glucose out of sunlight and atmospheric CO2.
Chemoplast: Makes glucose out of Hydrogen Sulfide.
Nitrogen Fixing Plastid: Makes ammonia from ATP and atmospheric Nitrogen and Oxygen.
Vacuole: Stores 15 collected compounds.
Toxin Vacuoles: Produces toxins (called OxyToxyNT).